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Rosacea

Definition
Rosacea is a non-infectious inflammatory condition of the facial skin.
Incidence, Age and SexUp to 10% of the population may be affected by rosacea at some stage in their life. It is an under diagnosed condition. The commonest age of onset is in the fourth and fifth decade. Any adult however may develop this condition at any age. It affects males and females with equal incidence.

Causes and Prevention
Rosacea appears more commonly in those with Celtic skin types. It can be hereditary. The red flushing which is one of the characteristics of the condition may be triggered by a number of different factors. Often these trigger factors will vary considerably from individual to individual. Some of the common trigger factors are:

• Hot food and drinks (temperature)
• Alcohol
• Caffeine
• Spicy foods
• Stress
• Temperature changes
• Sun exposure
• Wind exposure
• Embarrassment
These factors are potential aggravating factors but are not the cause of the condition.

Symptoms
After a period of intermittent facial flushing, the skin becomes persistently red with the development of tiny broken thread veins (telangiectasia) over the affected area. These flushing attacks can be extremely uncomfortable for some individuals with sensations ranging from burning to intense pain. Where the condition starts it tends to stay. The commonest area of involvement is on the cheeks. Other areas which may be involved include the nose, chin and central forehead.

Some rosacea sufferers may only experience facial flushing and redness, but the majority will also experience small outbreaks of acne-like spots within the affected area. These are often described as being small pimples although occasionally some individuals may develop larger pus-like spots.

Complications of the Disorder
Many people believe that their facial redness is purely a cosmetic problem and do not seek advice about it. However, it is important to treat this condition early to prevent long term side effects which include permanent thread veins (telangiectasia); rhinophyma (enlargement of the nose); persistent swelling (oedema) of the face or eye discomfort.

Tests
There are no specific tests for rosacea. The diagnosis is usually made clinically. Rosacea however can be confused with acne or seborrhoeic eczema (dermatitis). Some people however do have both rosacea and seborrhoeic eczema co-existing.

Treatment
Mild rosacea may benefit from reducing exposure to the trigger factors described above. However in practice avoidance of these trigger factors has very little benefit for the majority of sufferers.

In mild rosacea antibiotics applied to the skin (topical antibiotics) are commonly used. In general Metronidazole is used and needs to be applied sparingly to the whole affected area.
With severer disease, antibiotics by mouth are used. Antibiotics tend to improve the acne-like component of the disease within 8 weeks of treatment. If this is not achieved then a change of antibiotic or an alteration of dosage may be indicated. The flushing and redness tends to respond slowly to antibiotics often requiring at least a 6 month course of treatment.
Severe flushing may be difficult to control. Occasionally some patients may benefit from Clonidine to help to reduce the flushing attacks.

With severe cases of acne rosacea with many pustular lesions which has not responded to higher dose antibiotic treatment then a hospital only prescribable drug called Roaccutane can be considered. Roaccutane however has many potential side effects and therefore has to be considered carefully before usage.

Rhinophyma (gross enlargement of the nose) can be treated either surgically by a shaving type of operation which can be performed under local anaesthetic, or by reshaping of the nose using an ultrapulse CO2 laser. If this is required then the rosacea should be actively treated and brought under control before any surgical intervention is considered.
Outcome

Rosacea may be self-limiting burning itself out within a 4 to 5 year period. However some people may experience long term problems. Treatment is usually effective at bringing the condition under control, but recurrences may occur subsequently even after many years requiring further treatment.

When rosacea affects predominantly the nose there is a false belief that individuals may be alcoholics which is totally untrue. This can result in psychological distress which may require active help. Camouflage can be used to try and conceal the redness but in practice the key to managing rosacea is one of controlling the skin condition.

 
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